Tissue Protein Carbonylation in Aging: A Strategic Analysis of Age-Related Protein Modification
نویسندگان
چکیده
منابع مشابه
Construction and Analysis of Tissue-Specific Protein-Protein Interaction Networks in Humans
We have studied the changes in protein-protein interaction network of 38 different tissues of the human body. 123 gene expression samples from these tissues were used to construct human protein-protein interaction network. This network is then pruned using the gene expression samples of each tissue to construct different protein-protein interaction networks corresponding to different studied ti...
متن کاملProtein carbonylation.
Protein carbonylation is a type of protein oxidation that can be promoted by reactive oxygen species. It usually refers to a process that forms reactive ketones or aldehydes that can be reacted by 2,4-dinitrophenylhydrazine (DNPH) to form hydrazones. Direct oxidation of side chains of lysine, arginine, proline, and threonine residues, among other amino acids, in the ‘‘primary protein carbonylat...
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Aging is characterized by the progressive decline of biochemical and physiological function in an individual. Consequently, aging is a major risk factor for diseases like cancer, obesity, and type 2 diabetes. The cellular and molecular mechanisms of aging are not well understood, nor is the relationship between aging and the onset of diseases. One of the hallmarks of aging is a decrease in cell...
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Background - MaterialsAndMethods N;Results N;Conclusion N;
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ژورنال
عنوان ژورنال: Journal of Advances in Medical and Pharmaceutical Sciences
سال: 2019
ISSN: 2394-1111
DOI: 10.9734/jamps/2019/v20i330111